MiuraCV

Kazuki Miura

	Kazuki Miura
	Researcher ID
	Tel: 045-924-5245
	E-mail
	Assistant Professor, Laboratory for Chemistry and Life Science, Tokyo Institute of Technology
	Fields of interest: Chemical Biology, Biochemistry

Education

• Ph.D., in Bioresource Sciences; Nihon University, Kanagawa, JAPAN 2018
• M. Sc.,in Bioresource Sciences; Nihon University, Kanagawa, JAPAN 2015
• B. Sc., in Bioresource Sciences; Nihon University, Kanagawa, JAPAN 2013

Academic Career

• Research Associate of Laboratory for Biochemistry, Department of Applied Chemistry, Faculty of Science and Technology, Keio University, Kanagawa, JAPAN, 2018-2021
• Assistant Professor of Laboratory for Chemistry and Life Science, Tokyo Institute of Technology, Tokyo, JAPAN, 2020-present

Awards and Fellowship

• The Japanese Society of Applied Glycoscience, East Japan Branch, Young Scientist Award 2018
• GlycoTokyo 2017 Symposium, Poster Award
• The 66th Annual Meeting of Japanese Society of Applied Glycoscience, Poster Award 2017
• The Japan Society for Bioscience, Biotechnology, and Agrochemistry, Annual Meeting of Kanto Branch, Best Presentation Award 2017

Main Research Areas

• Chemical Biology
• Biochemistry

Professional Societies

• The Japan Society for Bioscience, Biotechnology, and Agrochemistry
• The Japanese Society for Chemical Biology
• The Japanese Society of Carbohydrate Research
• The Japanese Society of Applied Glycoscience
• The Japanese Association for Molecular Target Therapy of Cancer

Publication List　researcher ID

• “Requirement for C-mannosylation to be secreted and activated a disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS4)”, K. Miura, T. Suzuki, H. Sun, H. Takata, Y. Ishizawa, H. Mizuta, S. Simizu, Biochim. Biophys. Acta Gen. Subj. 1865 (3), 129833 (2021).
• “Identification of madangamine A as a novel lysosomotropic agent to inhibit autophagy”, K. Miura, S. Kawano, T. Suto, T. Sato, N. Chida, S. Simizu, Bioorg. Med. Chem. 34, 116041 (2021).
• “Development of Fluorescent Substrate for Glycan Processing Glycosidase, and Screening of the Novel Glycosidase Inhibitor”, K. Miura, W. Hakamata, Trends Glycosci. Glycotechnol. 32 (190), E201-E204 (2020)
• “Screening, synthesis, and evaluation of novel isoflavone derivatives as inhibitors of human Golgi β-galactosidase”, K. Miura, C. Onodera, M. Takagi, R. Koyama, T. Hirano, T. Nishio, W. Hakamata, Chem. Pharm. Bull. 68 (8), 753-761 (2020)
• “Development of specific fluorogenic substrates for human β-N-acetyl-D-hexosaminidase A for cell-based assays”, K. Miura, Y. Aoyama, Y. Natsu, R. Koyama, T. Hirano, T. Nishio, W. Hakamata, Chem. Pharm. Bull. 68 (6), 526-533 (2020)
• “Identification of vibsanin A analog as a novel HSP90 inhibitor”, K. Miura, W. Matsuki, A. Ogura, K. Takao, S. Simizu, Bioorg. Med. Chem. 28 (2), 115253 (2020).
• “Development of fluorogenic substrates of α-L-fucosidase useful for inhibitor screening and gene-expression profiling”, K. Miura, T. Tsukagoshi, T. Hirano, T. Nishio, W. Hakamata, ACS Med. Chem. Lett. 10 (9) 1309-1313 (2019).
• “Discovery of human Golgi β-galactosidase with no identified glycosidase using a QMC substrate design platform for exo-glycosidase”, K. Miura, W. Hakamata, A. Tanaka, T. Hirano, T. Nishio, Bioorg. Med. Chem. 24 (6), 1169-1375 (2016).