2022・2021
2022
-
-
-
-
- S. Noda, A. Yamada, Y. Asawa, H. Nakamura, T. Matsumura, H. Orimo, and M. Goseki-Sone,
“Characterization and Structure of Alternatively Spliced Transcript Variant of Human Intestinal Alkaline Phosphatase (ALPI) Gene”, J. Nutr. Sci. Vitaminol., accepted (2022).
- H. Kitamura, Y. Otake, N. Sugisawa, H. Sugisawa, T. Ida, H. Nakamura, S. Fuse
“Sequential Selective Introduction of Alcohols against Phosphorus Trichloride in a Continuous-Flow Reactor and Consideration of a Mechanism for Reduced Overreaction via the Addition of Imidazole”, Chem. Eur. J., 28, accepted (2022).
ChemCatChem., accepted (2022). DOI:10.1002/cctc.202200077
- 盛田大輝、中村浩之
“光反応を利用したタンパク質の化学修飾”, カレントレビュー, 43, 71-77 (2022).
- S. Koyama, H. Sato, H. Sugai, M. Murakoshi, T. Kobayashi, S. Usami, K. Ikeda, Y. Haga, K. Tsumoto, H. Nakamura, N. Hirasawa, K. Ishihara, H. Wada
“Effects of Salicylate Derivatives on Changes in Localization of H723R Pendrin Mutant Expressed in HEK293 Cells”, Auris Nasus Larynx, accepted (2022).
- K. Nakane, T. Niwa, M. Tsushima, S. Tomoshige, H. Taguchi, H. Nakamura, M. Ishikawa, S. Sato
“BODIPY Catalyzes Proximity‐Dependent Histidine Labelling”,
ChemCatChem., accepted (2022). DOI:10.1002/cctc.202200077
- R. Y. Utomo, S. Okada, A. Sumiyoshi, I. Aoki, H. Nakamura
“Detoxification by curcumin derivative via dissociation of amyloid β fibrils and its verification in Drosophila Alzheimer’s model”, RSC Adv., 12, 5027-5030 (2022). DOI:10.1039/D2RA00614F
- R. Y. Utomo, A. Sugie, S. Okada, K. Miura, H. Nakamura
“Detoxification by curcumin derivative via dissociation of amyloid β fibrils and its verification in Drosophila Alzheimer’s model”, Chem. Commun., 58, 2576-2579 (2022). DOI:10.1039/D1CC07000B
- M. Tsuda, T. Morita, H. Nakamura
“Synthesis of isoxazoloazaborines via Gold(I)-catalyzed propargyl aza-Claisen rearrangement/borylative cyclization cascade”, Chem. Commun., 58, 1942-1945(2022). DOI:10.1039/D1CC07002A
Highlighted in Synfacts Issue 05/Volume 18/2022
- M. Tsushima, S. Sato, K. Miura, T. Niwa, H. Taguchi, H. Nakamura
“Intracellular Photocatalytic-Proximity Labeling for Profiling Protein–Protein Interactions in Microenvironments”, Chem. Commun., 58, 1926-1929 (2022). DOI:10.1039/D1CC05764B
- A. R Jalilian, A. Shahi, I. P. Swainson, H. Nakamura, M. Venkatesh, J. A. Osso Jr
“Potential theranostic BNCT agents as multimodal radiopharmaceuticals”, Cancer Biother. Radiopharm., accepted (2022).
- T. Morita, H. Murakami, Y. Asawa, H. Nakamura
“Enantioselective Synthesis of Oxazaborolidines by Palladium-Catalyzed N–H/B–H Double Activation of 1,2-Azaborines”, Angew. Chem. Int. Ed., 61, e202113558 (2022). DOI:10.1002/anie.202113558
Highlighted in Synfacts Issue 03/Volume 18/2022
- H. Ueda, P. Wipf, H. Nakamura
“Synthesis of sp3-rich chiral bicyclo[3.3.1]nonanes for chemical space expansion and study of biological activities”, Bioorg. Med. Chem., 54, 116561 (2022). DOI:10.1016/j.bmc.2021.116561
- T.-H. Han, M. K. Park, H. Nakamura, H. S. Ban
“Capsaicin inhibits HIF-1α accumulation through suppression of mitochondrial respiration in lung cancer cells”, Biomed. Pharm., 146, 112500 (2022). DOI:10.1016/j.biopha.2021.112500
- G. Li, G. Yu, C. Wang, T. Morita X. Zhang, H. Nakamura
“Copper(I)-catalysed intramolecular hydroarylation-redox cross-dehydrogenative coupling of N-propargylanilines with phosphites”, Org. Biomol. Chem., 20, 113-116 (2022). DOI:10.1039/D1OB02091A
- H. Kashiwagi, S. Kawabata, K. Yoshimura, Y. Fukuo, T. Kanemitsu, K. Takeuchi, R. Hiramatsu, K. Nishimura, K. Kawai, T. Takata, H. Tanaka, T. Watanabe, M. Suzuki, S. Miyatake, H. Nakamura, M. Wanibuchi
“Boron neutron capture therapy using dodecaborated albumin conjugates with maleimide is effective in a rat glioma model”, Investigational New Drugs, 40, 255–264 (2022). DOI:10.1007/s10637-021-01201-7
2021
-
-
-
-
- Yanagie, M. Yanagawa, Y. Sakurai, K. Mouri, Y. Morishita, A. Shinohara, N. Dewi, Y. Nonaka, Y. Furuya, R. Mizumachi, Y. Murata, H. Nakamura, M. Suzuki, Y. Sakurai, H. Tanaka, S. Masunaga, K. Ono, T. Sugihara, M. Nashimoto, H. Yamauchi, M. Ono, J. Nakajima, H. Terada, H. Takahashi
“Tumour Growth Suppression in Rabbit Hepatic Cancer Model by Boron Neutron Capture Therapy with Liposomal Boron Delivery Systems”, In Vivo, 35(6), 3125-3135 (2021). DOI: 10.21873/invivo.12607
- Y. Asawa, S. Hatsuzawa, A. Yoshimori, K. Yamada, A. Katoh, H. Kouji, H. Nakamura
“Comprehensive Exploration of Chemical Space Using Trisubstituted Carboranes”, Sci. Rep., 11, 24101 (2021). DOI: 10.1038/s41598-021-03459-6
- Y. Tsuji, N. Nonoguchi, D. Okuzaki, Y. Wada, D. Motooka, Y. Hirota, T. Toho, N. Yoshikawa, M. Furuse, S. Kawabata, S.-I. Miyatake, H. Nakamura, R. Yamamoto, S. Nakamura, T. Kuroiwa, M. Wanibuchi
“Chronic pathophysiological changes in the normal brain parenchyma caused by radiotherapy accelerate glioma progression”, Sci. Rep., 11, 22110 (2021). DOI: 10.1038/s41598-021-01475-0
- Y. Asawa, K. Nishida, K. Domae, K. Kawai, H. S. Ban, H. Asami, J.-Y. Kohno, S. Okada, H. Tokuma, D. Sakano, S. Kume, M. Tanaka, H. Nakamura
“Carborane as an Alternative Efficient Hydrophobic Tag for Protein Degradation”,
Bioconjugate Chem., 32(11), 2377–2385 (2021). DOI: 10.1021/acs.bioconjchem.1c00431
- S. Okada, S. Takayasu, A. Sumiyoshi, I. Aoki, H. Nakamura
“MRI-based Glucose Assay Using Magnetic Nanoparticle Sensors”, Anal. Sci. 37, 12, 1765-1769 (2021) DOI: 10.2116/analsci.21P082
- S. Sato, M. Matsumura, H. Ueda, H. Nakamura
“Preparation of an antigen-responsive fluorogenic immunosensor by tyrosine chemical modification of the antibody complementarity determining region”, Chem. Commun., 57, 9760-9763 (2021). DOI: 10.1039/d1cc03231c
- G. Li, Y. Shao, Y. Pan, Y. Li, Y. Wang, L. Wan, K. Shao, S. Wang, H. Dong, X. W, X. Guo, W. Zhao, H. Nakamura
“Total synthesis and biological evaluation of 7-Hydroxyneolamellarin A as hypoxia-inducible factor-1α inhibitor for cancer therapy”, Bioorg. Med. Chem. Lett., 50, 128338 (2021). DOI:10.1016/j.bmcl.2021.128338
- R. Yudi Utomo, Y. Asawa, S. Okada, H. S. Ban, A. Yoshimori, J. Bajorath, H. Nakamura
“Development of curcumin-based amyloid β aggregation inhibitors for Alzheimer’s disease using the SAR matrix approach”, Bioorg. Med. Chem., 46, 116357 (2021). DOI:10.1016/j.bmc.2021.116357
- N. Sugisawa, H. Sugisawa, Y. Otake, R. V. Krems, H. Nakamura, S. Fuse
“Rapid and Mild One-Flow Synthetic Approach to Unsymmetrical Sulfamides Guided by Bayesian Optimization”, Chemistry Methods, accepted. DOI:10.1002/cmtd.202100053
- K. Umedera, T. Morita, A. Yoshimori, K. Yamada, A. Katoh, H. Koji, H. Nakamura
“Synthesis of Three-Dimensional (3D) (Di)azatricyclododecene Scaffold and its Application to Peptidomimetics”, Chem. Eur. J., 27(46), 11888-11894 (2021). DOI:10.1002/chem.202101440
- M. Tsuda, T. Morita, H. Nakamura
“Suzuki-Miyaura Cross-coupling of 3,4-disubstituted 5-bromoisoxazoles: An efficient access to trisubstituted isoxazoles”, Tetrahedron Lett., 75, 153185 (2021). DOI:10.1016/j.tetlet.2021.153185
- K. Nakane, S. Sato, T. Niwa, M. Tsushima, S. Tomoshige, H. Taguchi, M. Ishikawa, H. Nakamura
“Proximity Histidine Labeling by Umpolung Strategy Using Singlet Oxygen”, J. Am. Chem. Soc., 143(20), 7726–7731 (2021). DOI:10.1021/jacs.1c01626
- P. Singh, M. Kaur, K. Singh, G. Kaur, R. Meena, M. Kaur, B. Singh, A. Thakur, J. Sharma, A. Singh, M. Kumar, J. H. Yun, F. Nakagawa, M. Suzuki, H. Nakamura, A. Kumar
“Fluorescent Boron Carbide Quantum dots synthesized with a low-temperature solvothermal approach for boron neutron capture therapy”, Phys. E: Low-Dimens. Syst. Nanostructures, 132, 114766 (2021). DOI:10.1016/j.physe.2021.114766
- S. Fuse, K. Komuro, Y. Otake, H. Masui, H. Nakamura
“Rapid and Mild Lactamization Using Highly Electrophilic Triphosgene in a Micro-Flow Reactor”, Chem. Eur. J., 27(27), 7525-7532 (2021). DOI:10.1002/chem.202100059
- Y. Asawa, A. V. Arsent’eva, S. A. Anufriev, A. A. Anisimov, K. Y. Suponitsky, O. A. Filippov, H. Nakamura, I. B. Sivaev
“Synthesis of Bis(Carboranyl)amides 1,1’-μ-(CH2NH(O)C(CH2)n– 1,2-C2B10H11)2 (n = 0, 1) and Attempt of Synthesis of Gadolinium Bis(Dicarbollide)”, Molecules, 26(5), 1321 (2021). DOI:10.3390/molecules26051321
- 中村 浩之
「BNCTの薬剤と中性子の反応」、月刊インナービジョン特集号、36(2), 40-42 (2021).
- M. Tsuda, S. Fukuhara, T. Morita, H. Nakamura
“Synthesis of 4-Amino-5-allenylisoxazoles via Gold(I)-Catalyzed Propargyl Aza-Claisen Rearrangement”, Org. Biomol. Chem.,19, 1358 (2021). DOI:10.1039/D0OB02544E
- S. Ban, Y. Uto, H. Nakamura
“Hypoxia-inducible factor (HIF) inhibitors: a patent survey (2016-2020)”, Expert Opin. Ther. Pat., 31(5), 387-397 (2021). DOI:10.1080/13543776.2021.1874345
- T. Shimizu, N. Takahashi, V. J. Huber, Y. Asawa, H. Ueda, A. Yoshimori, Y. Muramatsu, H. Seimiya, H. Kouji, H. Nakamura, H. Oguri
“Design and synthesis of 14 and 15-membered macrocyclic scaffolds exhibiting inhibitory activities of hypoxia-inducible factor 1α”,
Bioorg. Med. Chem., 30, 115949 (2021). DOI:10.1016/j.bmc.2020.115949
-
-
-
-