東京工業大学　科学技術創成研究院　化学生命科学研究所　中村・岡田研究室

発表論文 (〜2000)

2000・1999・1998・1997・1996・1995・1994・1993・1992

2000

          1. H. Nakamura, H. Fukuda, F. Girard, T. Kobayashi, H. Nemoto, J. Cai, K. Yoshida, Y. Yamamoto,”In Vivo Evaluation of Carborane Gadolinium-DTPA Complex as an MR Imaging Boron Carrier”, Chem. Pharm. Bull. 48, 1034-1038 (2000). LINK
          2. H. Nakamura, M. Fujiwara, Y. Yamamoto,”A Practical Method for the Synthesis of Enantiomerically Pure 4-Borono-L-phenylalanine”, Bull. Chem. Soc. Jpn., 73, 231-235 (2000).
          3. H. Nakamura, H. Shibata, Y. Yamamoto, “Palladium Catalyzed Cyanoallylation of Activated Olefins”,Tetrahedron Lett., 41, 2911-2914 (2000). LINK
          4. B. Ming, H. Nakamura, Y. Yamamoto,”Preparation and application of polymer-supported chiral p-allylpalladium catalyst for the allylation of imines”, Tetrahedron Lett., 41, 131-134 (2000). LINK

1999

          1. H. Nakamura, H. Iwama, M. Ito, Y. Yamamoto,”Palladium(0) Catalyzed Cope Rearrangement of Acyclic 1,5-Dienes. Bis(p-allyl)palladium(II) Intermediate”, J. Am. Chem. Soc., 121 10850-10851(1999). LINK
          2. K.-Y. Rho, Y.-J. Cho, C.-M. Yoon, H. Nakamura,”Synthesis of a New Amphiphilic ortho-Carborane Derivative as a Potential BNCT Agent: 4-[N,N-Formyl-(ortho-carboranylmethyl)-amino]-benzoyl-L-glutamic Acid”, Tetrahedron Lett., 40, 4821-4824 (1999). LINK
          3. K. Aoyagi, H. Nakamura, Y. Yamamoto,”A Concise and Stereospecific One-Shot Synthesis of Bicyclo[3,3,1]nonenols from Dimethyl 1,3-Acetonedicarboxylate and Enals via the Sequential Michael Addition-Intramolecular Aldolization”, J. Org. Chem., 64, 4148-4151 (1999). LINK
          4. K. Nakamura, H. Nakamura, Y. Yamamoto,”Chiral p-Allylpalladium-Catalyzed Asymmetric Allylation: Replacement Allylstannanes by Allylsilanes”, J. Org. Chem., 64, 2614-2615 (1999). LINK
          5. H. Nakamura, Y. Yamamoto, Collect. Czech.”Novel Addition Reactions of Silyl- and Stannyl-ortho-carboranes to Carbonyl Compounds”, Chem. Commun., 64, 829-846 (1999). LINK
          6. H. Nemoto, J. Cai, H. Nakamura, M. Fujiwara, Y. Yamamoto,”The Synthesis of Carborane Gadolinium-DTPA Complex for Boron Neutron Capture Therapy”, J. Organomet. Chem., 581, 170-175 (1999). LINK
          7. H. Nakamura, K. Aoyagi, Y. Yamamoto,”Synthetic Utility of o-Carborane: Novel Protective Group for Aldehydes and Ketones”, J. Organomet. Chem., 574, 107-115 (1999). LINK
          8. A. T. Tatham, H. Nakamura, E. C. Wiener, Y. Yamamoto,”Relaxation properties of a dual-labeled probe for MRI and neutron capture therapy”, Mag. Res. Med., 42, 32-36 (1999). LINK

1998

          1. H. Nakamura, Y. Yamamoto,”The Renaissance of p-Allylpalladium-catalyzed Organic Synthesis”, J. Syn. Org. Chem. Jpn., 56, 395-405（1998）.
          2. J.-G. Shim, H. Nakamura, Y. Yamamoto,”Palladium Catalyzed Regioselective b-Acetonation-a-Allylation of Activated Olefins in One Shot”, J. Org. Chem., 63, 8470-8474 (1998). LINK
          3. H. Nakamura, M. Fujiwara, Y. Yamamoto,”A Concise Synthesis of Enantiomerically Pure L-(4-Boronophenyl)alanine from L-Tyrosine”, J. Org. Chem., 63, 7529-7530 (1998). LINK
          4. H. Nakamura, M. Sekido, M. Ito, Y. Yamamoto,”Palladium-Catalyzed Alkoxyallylation of Activated Olefins”, J. Am. Chem. Soc., 120, 6838-6839 (1998). LINK
          5. H. Nakamura, K. Nakamura, Y. Yamamoto,”Catalytic Asymmetric Allylation of Imines via Chiral Bis-p-allylpalladium Complexes”, J. Am. Chem. Soc., 120, 4242-4243 (1998). LINK
          6. H. Nakamura, K. Aoyagi, Y. Yamamoto,”Tetrabutylammonium Fluoride Promoted Novel Reactions of o-Carborane: Inter- and Intramolecular Additions to Aldehydes and Ketones and Annulation via Enals and Enones”, J. Am. Chem. Soc., 120, 1167-1171 (1998). LINK

1997

          1. H. Nakamura, J-G. Shim, Y. Yamamoto,”Amphiphilic Catalytic Allylating Reagent, Bis-p-allylpalladium Complex”, J. Am. Chem. Soc., 119, 8113-8114 (1997). LINK
          2. H. Nakamura, M. Sekido, Y. Yamamoto,”Synthesis of Carboranes Containing Azulene Framework and In vitro Evaluation as Boron Carriers”, J. Med. Chem., 40, 2825-2830 (1997). LINK
          3. H. Nakamura, K. Aoyagi, Y. Yamamoto,”o-Carborane as a Novel Protecting Group of Aldehydes and Ketones”, J. Org. Chem., 62, 780-781 (1997). LINK
          4. H. Nakamura, K. Aoyagi, B. Singaram, J. Cai, H. Nemoto, Y. Yamamoto,”A Novel [3+2] Annulation between o-Carboranyltrimethylsilane and Conjugated Carbonyl Compounds”, Angew. Chem. Int. Ed. Engl., 36, 367-369 (1997). LINK
          5. J. Cai, H. Nemoto, H. Nakamura, B. Singaram, Y. Yamamoto,”Tetrabutylammonium Fluoride Promoted Regiospecific Reaction of Trimethylsilyl-o-carborane with Carbonyl Compounds”, Advances in Boron Chemistry, Ed. W. Siebert, The Royal Society of Chemistry, 112-115 (1997).
          6. F. Girard, H. Nakamura, H. Fukuda, Y. Yamamoto, K, Yoshida,”Rat Tumor Imaging with B-10 Carborane Gadolinium Complex”, Recent Advances in Biomedical Imaging, Ed. Y. Ishii et al. Elsevier Science, 201-207 (1997).
          7. H. Nakamura, M. Sekido, Y. Yamamoto,”Synthesis of Carborane Containing Azlene Framework Using New Palladium Catalyzed Reaction”, Advances in Neutron Capture Therapy, Eds. B. Larsson, J. Crawford, R. Weinreich, Plenum Press, New York, 42-45 (1997).
          8. F. Girard, H. Fukuda, H. Nakamura, Y. Yamamoto, K. Yoshida,”MR Imaging of Rat Tumor with 10B Carborane Gadolinium Complex”, Advances in Neutron Capture Therapy, Eds. B. Larsson, J. Crawford, R. Weinreich, Plenum Press, New York, 271-275 (1997).
          9. Y. Yamamoto, J. Cai, H. Nemoto, H. Nakamura, F. Girard, K. Yoshida, H. Fukuda,”A New Synthetic Method of All Carboxylate-free DTPA Derivatives and Its Application to the Synthesis of Gd-Carborane Complex”, Advances in Neutron Capture Therapy, Eds. B. Larsson, J. Crawford, R. Weinreich, Plenum Press, New York, 436-439 (1997).

1996

          1. J. Cai, H. Nemoto, H. Nakamura, B. Singaram, Y. Yamamoto,”Tetrabutylammonium Fluoride Promoted Regiospecific Reactions of Trimethylsilyl-o-Carborane with Aldehydes”, Chem. Lett., 9, 791-792 (1996).
          2. H. Nakamura, H. Iwama, Y. Yamamoto,”Palladium and Platinum Catalyzed Addition of Aldehydes and Imines with Allylstannanes. Chemoselective Allylation of Imines in the Presence of Aldehydes”, J. Am. Chem. Soc., 118, 6641-6647 (1996). LINK
          3. H. Nakamura, H. Iwama, Y. Yamamoto,”Unprecedented Highly Chemoselective Allylation of Imines in the Presence of Aldehydes via Palladium Catalyzed Allylstannane Reaction”, Chem. Commun., 1459-1460 (1996). LINK
          4. Y. Yamamoto, J. Cai, H. Nakamura, N. Sadayori, H. Nemoto,”Netropsin and Distamycin Analogues Bearing ortho-Carborane”, Cancer Neutron Capture Therapy, Ed. Y. Mishima, Plenum Press, New York, 177-182 (1996).

1995

          1. H. Nakamura, N. Asao, Y. Yamamoto,”Palladium and Platinum-catalyzed Addition of Aldehydes with Allylstannanes”, J. Chem. Soc. Chem. Commun., 1273-1274 (1995). LINK
          2. Y. Yamamoto, J. Cai, H. Nakamura, N. Sadayori, N. Asao, H, Nemoto,”Synthesis of Netropsin and Distamycin Analogues Bearing o-Carborane and Their DNA Recognition”, J. Org. Chem., 60, 3352-3357 (1995).

1994

          1. H. Nakamura, N. Sadayori, M. Sekido, Y. Yamamoto,”Palladium Catalyzed Addition of 1-Carboranyltributyltin to Aldehydes”, J. Chem. Soc. Chem. Commun., 22581-2582 (1994).
          2. Y. Yamamoto, H. Nemoto, H. Nakamura, S. Iwamoto,”Synthesis of New 10B Carriers and Their Selective Uptake by Cancer Cells”, Current Topics in the Chemistry of Boron Ed. G. Kabalka, The Royal Society of Chemistry, 149-154 (1994).

1993

          1. Y. Yamamoto, H. Nakamura, H. Nemoto,”Synthesis and Biological Properties of Carboranylaziridine”, Advances in Neutron Capture Therapy, Eds. A.H. Soloway, R.F. Barth, D.E. Carpenter, Plenum Press, New York, 305-308 (1993).
          2. Y. Yamamoto, H. Nakamura,”1-Carboranyl-3-methylaziridino-2-propanol. Synthesis, Selective Uptake by B-16 Melanoma, and Selective Cytotoxicity toward Cancer Cells”, J. Med. Chem., 36, 2232-2234 (1993).LINK
          3. Y. Yamamoto, N. Asao, M. Meguro, N. Tsukada, H. Nemoto, S. Sadayori, J. Gerald Wilson, H. Nakamura,”Regio- and Stereo-selective Ring Opening of Epoxides with Amide Cuprate Reagents”, J. Chem. Soc. Chem. Commun., 1201-1203 (1993). LINK
          4. Y. Yamamoto, S. Takamatsu, H. Nakamura,”Boron-11 NMR of Boron Compounds in the Presence of Cancer Cells”, J. Magn. Res. Series B, 101, 198-200 (1993).

        H. Nemoto, S. Iwamoto, H. Nakamura, Y. Yamamoto,”A New Water-soluble p-Boronophenylalanine Derivative for Neutron Capture Therapy”, Chem. Lett., 465-468 (1993).

1992

        1. Y. Yamamoto, T. Seko, H. Nakamura, H. Nemoto,”Synthesis of Carboranes Containing Nucleoside Bases”, Heteroatom Chem., 3, 239-244 (1992). LINK
        2. H. Nemoto, J. G. Wilson, H. Nakamura, Y. Yamamoto,”Polyols of a Cascade Type as a Water-Solubilizing Element of Carborane Derivatives for Boron Neutron Capture Therapy”, J. Org. Chem., 57, 435 (1992). LINK
        3. Y. Yamamoto, T. Seko, H. Nakamura, H. Nemoto, H. Hojo, N. Mukai, Y. Hashimoto,”Synthesis of Carboranes Containing Nucleoside Bases. Unexpectedly High Cytostatic and Cytocidal Toxicity toward Cancer Cells”, J. Chem. Soc. Chem. Commun., 157-158 (1992).LINK

         

           

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